You probably don’t need a study to tell you this but here you go.

Glaucoma patients taking topical medication have more ocular surface disease than non-glaucoma patients.
study of over 200 eyes using topical glaucoma medication gauged the level of ocular surface disease by using four outcomes measures: TBUT, corneal staining, tear meniscus height, and the OSD symptom questionnaire index (OSDI). Fifty-one control eyes were used for comparison.
The conclusion: Ocular surface disease was more prevalent in the eyes taking topical glaucoma medications. The main factors impacting OSD were drops with preservatives, longer treatment duration, and older age. (via)

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